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Current concerns about low level impurities exacerbated by issues like the discovery of nitrosamine impurities in medicines.2. , have led to a higher sensitivity to change and the risk of unknown threats.

Unknowns are inertial (hence regulations can be enablers); and there are also clear opportunities and support to try and test new ideas and processes e.g.A combination of developing science and clear and joined up regulation e.g.pharmacopeia and guidance, could help both the manufacturers and the biogenic solvent supply chain.

Very clear and appropriate specifications and standards could help to accelerate the investment in and development of biogenic solvents, transitions, and approvals..It was noted that there are streams of scientific development in Al models which can help predict the production of harmful impurities and detect these impurities cheaply at parts per billion and parts per trillion levels.. Standards are not just set by regulators.

Any party that sets specifications helps to create a myriad of different standards.

Consistent requirements across jurisdictions and customers could accelerate progress..These technologies can be more compact and manufactured in factories, offering a scalable and financially feasible solution compared to traditional large-scale nuclear projects.. 2.

Repowering coal:.A significant focus of the episode is on the '.

project, where existing coal plants are repurposed by replacing coal boilers with advanced nuclear heat sources.This approach leverages existing infrastructure and transmission lines, drastically reducing the need for new construction and minimising community disruption.. 3.